A simple, precise and accurate UV spectrophotometric method has been developed for estimation of saroglitazar in bulk and tablet dosage form. In this method saroglitazar shows λmax at 294 nm using ethanol as a solvent. The responses were linear in the range of 10-70 μg/ml. The regression equation of the calibration graph and correlation coefficient were found to be y = 0.016x - 0.005 and 0.9998 respectively. The recovery of the drug from the sample was ranged between 99.10% and 101.23%. The proposed method was validated as per ICH Q2 (R1) guidelines for precision, linearity, accuracy and recovery. The %RSD values for both intraday and interday precision were less than 2.0. The limit of detection (LOD) and limit of quantification (LOQ) were found to be 0.186 μg/ml and 0.563 μg/ml respectively by simple UV spectroscopy.
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